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HS-LS1-1

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HS-LS1-1 From Molecules to Organisms: Structure & Processes
Students who demonstrate understanding can: Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins, which carry out the essential functions of life through systems of specialized cells.
Clarification Statement: Emphasis is on the conceptual understanding that DNA sequences determine the amino acid sequence, and thus, protein structure. Students can produce scientific writings, oral presentations and or physical models that communicate constructed explanations.
Assessment Boundary: Assessment does not include identification of specific cell or tissue types, whole body systems, specific protein structures and functions, or the biochemistry of protein synthesis.
Crosscutting Concepts	Science & Engineering Practices	Disciplinary Core Ideas
Structure and Function: Investigating or designing new systems or structures requires a detailed examination of the properties of different materials, the structures of different components, and connections of components to reveal its function and/or solve a problem.	Constructing Explanations (for science) and Designing Solutions (for engineering): Constructing explanations and designing solutions in 9–12 builds on K–8 experiences and progresses to explanations and designs that are supported by multiple and independent student- generated sources of evidence consistent with scientific ideas, principles, and theories. Construct an explanation based on valid and reliable evidence obtained from a variety of sources (including students’ own investigations, models, theories, simulations, peer review) and the assumption that theories and laws that describe the natural world operate today as they did in the past and will continue to do so in the future.	Structure and Function: Systems of specialized cells within organisms help them perform the essential functions of life. All cells contain genetic information in the form of DNA molecules. Genes are regions in the DNA that contain the instructions that code for the formation of proteins, which carry out most of the work of cells.